AMR Control 2019–20

ONLINE EDITION

Contents

05 Infection Prevention and Control takes priority for AMR Dr Jean Carlet, President, and Garance Upham, Vice President, World Alliance Against Antibiotic Resistance (WAAAR) and Co-Editor-in-Chief, AMR Control

 

GLOBAL GOVERNANCE

08 Global governance to tackle antimicrobial resistance: The way forward Dr Haileyesus Getahun, Director, UN Interagency Coordination on Antimicrobial Resistance, Division of Antimicrobial Resistance, World Health Organisation and Dr Hanan Balkhy, Assistant Director General, Antimicrobial Resistance, Division of Antimicrobial Resistance, World Health Organisation PDF

10 Interview with Dame Sally Davies, Chief Medical Officer, England PDF

 

R&D POLICIES

16 Public investments in R&D for new antibiotics: A call for smart  and bold leadership Dr Clemens Martin Auer, Special Envoy for Health, Austrian Federal Ministry of Health; Vinzent Rest, Deputy Head, Department of Pharmacoeconomics, Austrian Federal Ministry of Health and Dr Katharina Hawlik, supported the Austrian Federal Ministry of Health during the EU Council Presidency of Austria PDF

 

20 The Global AMR R&D Hub – Enhancing the international coordination of antimicrobial resistatance research and development Dr Jennie Hood, Scientific Programme Officer, Global AMR R&D Hub; Dr Elmar Nimmesgern, Secretariat Lead, Global AMR R&D Hub, and Dr Marit Ackermann, Policy Officer, Global Health Research, Federal Ministry of Education and Research, Germany and Chair of the Global AMR R&D Hub Board of Members PDF

 

24 R&D for children’s  antibiotics – a wake-up call Dr Seamus O’Brien, R&D Director, GARDP; Professor Mike Sharland, Paediatric Infectious Diseases Unit, St George’s, University of London, UK and Professor Theoklis Zaoutis, Professor of Pediatrics and Epidemiology, University of Pennsylvania, USA and Chief Scientific Officer, Penta PDF

 

27 Phage therapy: A promising weapon in the global superbug crisis Dr Steffanie Strathdee, Associate Dean of Global Health Sciences, Harold Simon Professor of Medicine and Co-Director, Center for Innovative Phage Applications and Therapeutics, University of California San Diego, USA, and co-author of The Perfect Predator: A Scientist’s Race to Save Her Husband from a Deadly Superbug, with husband, Tom Patterson PDF

 

NATIONAL AND REGIONAL GOVERNANCE

30 The One Health approach and public education and awareness-raising activities in Japan Nobuaki Matsunaga, Chief, Clinical Epidemiology division, AMR Clinical Reference Center, National Center for Global Health and Medicine Hospital, Tokyo, Japan; Yoshiaki Gu, Chief, Information and Education division, AMR Clinical Reference Center, National Center for Global Health and Medicine Hospital, Tokyo, Japan and Norio Ohmagari, Director, AMR Clinical Reference Center, National Center for Global Health and Medicine Hospital, and Deputy Director General, National Center for Global Health and Medicine Hospital, Tokyo, Japan PDF

36 Antibiotic resistance and One Health: A mapping project in KwaZulu-Natal, South Africa Dr Sabiha Essack, South African Research Chair in Antibiotic Resistance and One Health,  University of KwaZulu-Natal, Durban, South Africa PDF

38 The implementation progress of the National Action Plan to contain antimicrobial resistance in China Professor Yonghong Xiao, Vice-Director, State Key Laboratory for Diagnosis & Treatment of Infectious Diseases, The First Affiliated Hospital School of Medicine, Zhejiang University, Hangzhou, China PDF

 

INFECTION PREVENTION AND CONTROL

39 The urgency of an infection prevention and control bundle against AMR – A proposal Elias Tannous, Lead, Infection Prevention and Control, Cleveland Clinic Abu Dhabi, United Arab Emirates,  and Founder, Arab Countries Infection Control Network   PDF

43 Japan Nosocomial Infections Surveillance (JANIS): From a national AMR surveillance system to an international collaboration Dr Koji Yahara, Senior investigator, Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan; Dr Sirenda Vong Program Area Manager, Health Emergency Information and Risk Assessment, Department of Health Emergencies, World Health Organization Regional Office for South-East Asia, New Delhi, India; Professor Visanu Thamlikitkul, Director, WHO Collaborating Centre for Antimicrobial Resistance Prevention and Containment, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Dr Rujipas Sirijatuphat, Assistant Professor, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand; Dr John Stelling Co-Director, WHO Collaborating Centre for Surveillance of Antimicrobial Resistance, Brigham and Women’s Hospital, Boston, MA, USA; Dr Aki Hirabayashi ( Researcher, Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan; Dr Keigo Shibayama (, Director, Department of Bacteriology II, National Institute of Infectious Diseases, Tokyo, Japan; Dr Motoyuki Sugai, Director, Antimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan and Norifumi Shigemoto, Deputy Director, Infectious Disease Control Division, Health Service Bureau, Ministry Health, Labour and Welfare, Tokyo, Japan. PDF

48 Better AMR control: Learning from experiences with HIV and Ebola about how to improve infection prevention in health settings  Dr David Gisselquist and Simon Collery, independent consultants on HIV, whose joint website, Don’t Get Stuck with HIV, offers advice about how to avoid blood-borne risks PDF

52 Infection prevention and control to reduce the risk and burden of AMR Professor Alessandro Cassini, Technical Officer, Infection and Prevention Control Global Unit, World Health Organization and Professor Benedetta Allegranzi, Coordinator, Infection and Prevention Control Global Unit, World Health Organization PDF

56  EU-JAMRAI: Europe fostering synergies to reduce the burden of AMR: what is EU doing to support Member States? Céline Pulcini, Ministry of Health, Paris, France, Jean-Baptiste Rouffet, Advisor to EU-JAMRAI Coordinator, France, and Marie-Cécile Ploy, EU-JAMRAI Coordinator, INSERM, Limoges, France on behalf of the JAMRAI work package leaders and the JAMRAI partners PDF

 

DIAGNOSTICS AND VACCINES

58 How next-generation sequencing can address the antimicrobial resistance challenge Dr Etienne Ruppé Associate Professor, University Paris Diderot and INSERM IAME Research Center, Paris, France; Dr Johan Bengtsson-Palme, Assistant Professor, Centre for Antibiotic Resistance Research at University of Gothenburg, Sweden; Dr Yannick Charretier, Postdoctoral researcher at the Genomic Research laboratory, Geneva University Hospitals, Switzerland and Professor Jacques Schrenzel, Head, Genomic Research Laboratory and Laboratory of Bacteriology, Geneva University Hospitals, Switzerland PDF

64 Vaccines: Frontline weapons in the fight against antimicrobial resistance Dr Seth Berkley, CEO, Gavi, the Vaccine Alliance PDF

 

GLOBAL HEALTH SECURITY

67 Armed conflicts and antimicrobial resistance: A deadly convergence Dr Louis-Patrick Haraoui, Assistant Professor, Department of Microbiology and Infectious Diseases, Faculty of Medicine and Health Sciences, Université de Sherbrooke, Québec, Canada; Dr Annie Sparrow, Assistant Professor, Icahn School of Medicine at Mount Sinai, New York, USA; Professor Richard Sullivan, Institute of Cancer Policy, Conflict & Health Research Group, King’s College London, UK; Professor Gian-Luca Burci, Adjunct Professor of International Law, Graduate Institute of International and Development Studies, Geneva, Switzerland; Dr Omar Dewachi, Associate Professor, Department of Anthropology, Rutgers University, New Brunswick, New Jersey, USA; Dr Ghassan Abu-Sittah, Assistant Professor of Surgery, Head of Division of Plastic & Reconstructive Surgery, American University of Beirut Medical Center, co-Director, Conflict Medicine Program, Global Health Institute, American University of Beirut, Lebanon, Honorary Senior Clinical Lecturer, Queen Mary University of London, UK and Professor Vinh-Kim Nguyen, Professor of Anthropology and Sociology, Graduate Institute of International and Development Studies, Geneva, Switzerland PDF

72 The experience of the US Department of Homeland Security in fostering public-private partnerships in public health including the use of Artificial Intelligence to enhance antimicrobial resistance surveillance and treatment Tammy Padilla, Program Manager, Public-Private Analytic Exchange Program, Department of Homeland Security, Office of Intelligence and Analysis, Washington DC, USA and Dr Chandra Pauline Dinakar Daniel, 2018 Researcher, Department of Homeland Security, Public-Private Analytic Exchange Program and Consultant, National Black Leadership Commission on AIDS, Research and Evaluation, New York, USA PDF

 

SANITATION AND THE ENVIRONMENT

76 Tackling AMR starts with the environment Amit Khurana, Programme Director, Food Safety and Toxins, Centre for Science and Environment, New Delhi, India and Rajeshwari Sinha, Deputy Programme Manager, Food Safety and Toxins, Centre for Science and Environment, New Delhi, India PDF

81 Intensive livestock production and meat processing: The workers’ fight for protection against antimicrobial resistance James Ritchie, Assistant General Secretary, International Union of Food Workers (IUF), Geneva, Switzerland PDF

 

TUBERCULOSIS

88 In the era of AMR, Tuberculosis is a priority! A discussion with Dr Soumya Swaminathan, WHO Chief Scientist, and former Deputy Director-General. PDF

94 Tackling drug-resistant tuberculosis is central to global efforts to combat antimicrobial resistance  Lice Y Gonzalez-Angulo, Technical Officer, Laboratories, Diagnostics & Drug Resistance Unit, Dr Anna Dean, Technical Officer, TB Monitoring & Evaluation Unit, Dr Fuad Mirzayev,  Medical Officer, Laboratories, Diagnostics & Drug Resistance Unit, Dr Alexei Korobitsyn, Technical Officer, Laboratories, Diagnostics & Drug Resistance Unit, Dr Gilpin, Senior Scientist, Laboratories, Diagnostics & Drug Resistance Unit, Dr Ernesto Jaramillo, Medical Officer, Laboratories, Diagnostics & Drug Resistance Unit, Hannah Monica Dias, Technical Officer, Policy, Strategy, Innovations Unit, Dr Karin Weyer, Coordinator Senior Scientist, Laboratories, Diagnostics & Drug Resistance Unit, and Dr Tereza Kasaeva, Director, Global TB Programme, World Health Organization, Geneva, Switzerland PDF

 

STEWARDSHIP

101 The need for global guidance on antibiotic stewardship in dentistry Susie Sanderson OBE), President, British Dental Association and Professor David M Williams,  Professor of Global Oral Health, Queen Mary University of London, UK PDF